Elevated Brownies Recipe | Download for FREE!

Share this
Medically reviewed by
shutterstock 1633792807 scaled

Table of Contents

THC, the primary psychoactive compound in cannabis, exists in many variations. Some variations of the cannabinoid naturally occur at low concentrations within the cannabis plant, while others – like traditional delta-9 THC – are abundant.


So, how can you get higher amounts of low-concentration THC variants, like delta-8 or delta-10? What if you want to feel the effects of low-concentration cannabinoids?


It’s simple: you chemically convert cannabis compounds to create these THC variants, also known as THC isomers.


Here, we’ll explain what isomers of THC are, overview the different THC variants, and explore THC isomers’ legality.

What Are THC Isomers?


THC isomers, also known as THC variants, are compounds with the same chemical formula as THC but a different arrangement of atoms.


In the cannabis world, a THC isomer generally refers to a THC variant that manufacturers have chemically modified to produce in higher concentrations


These variants, like delta-8 and delta-10, have the same chemical formula as delta-9 THC but with a different atomic structure. 

How Do Professionals Make THC Isomers?


For THC variants like delta-8 and delta-10 that exist at low concentrations in the cannabis plant, manufacturers require extensive chemical processes to turn other cannabis compounds into these THC isomers. This chemical process is called isomerization.


Legally, isomerization involves chemically modifying hemp-derived CBD. So how are THC isomers like delta-8 and delta-10 THC made from CBD by manufacturers?


  • Isolate CBD from hemp using solvent or CO2 extraction.
  • Use acids to convert the extracted CBD into a THC variant by rearranging the molecules through the formation of new chemical bonds.
  • After rearranging the molecules, another compound, like delta-8 or delta-10, is formed.

Are THC and CBD isomers? CBD has the same molecular formula as THC, just arranged differently. Therefore, they are considered isomers.

What is the Difference Between Delta 8, 9 and 10?


Now, let’s get into the activities of different isomers of THC. Also known as THC variants, these compounds produce various effects when consumed. 


While different marijuana compounds affect people differently, there is a consensus (and science) behind what each THC variant does.


So what are the most popular THC variants and what are their effects?



Delta-8 THC is naturally derived from cannabis plants and is a chemical analog of delta-9 THC. The cannabinoid is slightly structurally different from delta-9 and has a lower affinity for CB1 receptors, making it less psychoactive (approximately two-thirds as potent) than delta-9 THC.


Studies suggest that delta-8 consumers experience relaxation, euphoria, pain relief, and reduced inflammation. Delta-8 may provide many therapeutic benefits of traditional THC without the unwanted effects. In one study, a participant described delta-8 THC as “delta 9’s nicer younger sibling.” 


Compared to delta-9 THC, delta-8 is less likely to cause anxiety or paranoia. 



Delta-9 THC is the traditional THC variant found in abundance in the cannabis plant. Basically, delta-9 is what gets you high in classic cannabis products.


Delta-9 binds with CB1 receptors and is more potent than THC variants like delta-8 and delta-10.


Delta-9 has antiemetic, appetite stimulation, and analgesic properties. This means that it’s used as a treatment for nausea, boosting appetite, and chronic pain. 


Delta-9 also helps treat seizures, glaucoma, PTSD, and more. In patients with anxiety or depression, delta-9 may worsen the symptoms of these ailments.


While delta-9 has been the most researched THC variant, other THC variants may provide the same therapeutic benefits.


LEARN MORE: How Is It Legal to Buy Delta-9 Products Online?



Professionals naturally derive delta-10 THC from cannabis plants and is a chemical analog of delta-9 THC. 


This cannabinoid has less affinity for CB1 receptors than delta-8, making it less psychoactive than delta-8. However, delta-10 still produces mild psychoactive and euphoric effects.


Consumers find delta-10 to provide an uplifting, “daytime” high. Delta-10 consumers report stress-relieving effects, a sense of calm, and boosts of energy and motivation. 


If you are interested in a mild high or suffer from mental health ailments like anxiety and depression, delta-10 might be the best THC option for you.

Are THC Isomers Safe?


Any potential risks concerning THC isomers don’t come from the cannabinoid itself. Potential risks come from the additives and contaminants that join the product in the manufacturing process.


If you are interested in buying THC isomers like delta-8 and delta-10, look for credible retailers that provide third-party testing


When consumers purchase products online or in unlicensed stores, these products are more likely to be contaminated or untested.

Where Are THC Isomers Legal?


Let’s go over THC isomers legality. The 2018 Farm Bill indirectly legalized the sale of hemp-derived THC isomers, making them widely accessible. 


Unlike traditional delta-9 THC which is federally illegal, THC isomers are legal in most US states – except the states that have made specific laws to prohibit them. 



In other words, the legality of THC isomers depends on two factors:


  • If THC isomers like delta-8 or delta-10 are hemp-derived, they are federally legal. Hemp refers to cannabis containing 0.3% or less THC. THC isomers derived from any cannabis plant with more than 0.3% THC will only be legal in adult-use states.
  • Even if these THC variants are hemp-derived and federally legal, a state can make unique laws to prohibit THC isomers.

Is delta-8 legal in your state? This article will help you to find out. States are trying to keep up with the newfound legality of THC, so keep an eye on changing laws.

Elevate Your Weed Game


Are you interested in legal, third-party-tested cannabis products? The safest bet is always to purchase medical marijuana products from your local dispensary. 


So how can you do that? If you live in an MMJ state, you’ll need your medical marijuana card.


Luckily, MMJ cards are our specialty here at Elevate Holistics. With our hassle-free, straightforward process to get medical marijuana certification, you’ll be in a dispensary in no time. 


How does it work? Our process is 100% online and secure. After booking your appointment and filling out your forms, we’ll connect you with a certified doctor via video chat for MMJ approval. 


It really is that simple.

Experience the benefits of MMJ.

Get your medical card 100% online, 100% hassle-free -- within minutes.

Get Your MMJ Card Right From Home

Elevate Holistics’ process is quick, affordable, and done entirely online. It’s never been so easy.

About the author

Ally Hilbert is the Content and SEO Manager here at Elevate Holistics, working to publish and run Elevate’s blogs and landing pages, as well as conduct keyword research, competitor analysis, and more. After having brain surgery at the age of 17, Ally became fascinated with medical cannabis and its benefits, and, at 18, had her first CBD-related piece published. Today, she’s been writing about cannabis for the past six years, and simply can’t think of a better company to get to do it for. When she’s not writing or editing, Ally’s side-by-side with her pup Sadie in Seattle.
Related Posts
shutterstock 2141544657 scaled

THC vs THCA: Knowing the Differences

Cannabis consumers who have read anything about marijuana must have come across THC. You might even have read about CBD, terpenes, potency, and other cannabis-related

shutterstock 1257911146 scaled

What is CBG Good For?

CBG is one of the many cannabinoids found in the cannabis plant. However, as a minor cannabinoid, this compound is often forgotten about — or

shutterstock 1902106630 scaled e1666361985745

Is CBD Legal in Missouri?

The availability of CBD in Missouri is ideal for those wanting to experience its therapeutic benefits. Finding quality and safe CBD products is trickier than

Ready To Get Your MMJ Card?

Approval in 30-minutes or less!

Scroll to Top


elevate services

Unlock Our Secret Recipe!

Get ready to impress your friends and family with our top-secret recipe. Fill the form bellow

By clicking “Accept All”, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. Privacy Policy.